Running without air filters will not prolong engine life. Nor will it make it run better. Ideally, smoothing the air coming into the carbs will give you the best throttle response. Velocity stacks will not do that. For the really inclined, providing cold air to the carbs from in front of the engine would be the best yet, as it is denser and would provide better O2 content.
Leave the slide spring alone. It allows the slide diaphragm to respond to the engine demands properly. Increasing compression and fitting a higher lift cam may give you the "snap" you're looking for, but messing with the spring calibration will not.
If you go this route, plan on at least making the mains richer. You'll have to figure that out as you go. each application would be different.